課程資訊
課程名稱
 臨床藥品動態學
Clinical Pharmacokinetics 
開課學期
 106-1 
授課對象
 醫學院  藥學系  
授課教師
 林君榮 
課號
 CliPhm5017 
課程識別碼
 451 U0360 
班次
  
學分
 2.0 
全/半年
 半年 
必/選修
 必修 
上課時間
 星期四8,9(15:30~17:20) 
上課地點
 基醫406 
備註
 限本所學生與藥學系五年級以上學生修課。與胡幼圃、林欣儀、徐莞曾、吳建志、林淑文、林慧玲、沈麗娟合授
限學士班五年級以上
總人數上限：40人 
Ceiba 課程網頁
 http://ceiba.ntu.edu.tw/1061CliPhm5017_ 
課程簡介影片
 
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課程概述

CLINICAL PHARMACOKINETICS IS A CONTINUED COURSE FOR BIOPHARMACEUTICS AND PHARMACOKINETICS. SOME OF THE INFORMATION AND CONCEPTS FROM MATHEMATICS AND ELEMENTARY PHARMACOKINETICS WILL BE REVIEWED OR DEVELOPED AS NEEDED, BUT THE BALANCE OF PREREQUISITE MATERIAL WILL BE THE STUDENT’S RESPONSIBILITY. READINGS AND HOMEWORK WILL BE ASSIGNED, OR MAY BE SUGGESTED TO IMPROVE THE LEARNING EFFICIENCY OF STUDENTS. 

課程目標
 THE MAJOR PURPOSE OF THIS COURSE IS TO TEACH STUDENTS HOW TO SOLVE PHARMACOKINETIC AND/OR PHARMACODYNAMIC PROBLEMS ENCOUNTERED IN CLINICAL PRACTICE 
課程要求
 PREREQUISITES: BIOPHARMACEUTICS AND PHARMACOKINETICS. STUDENTS SHOULD BE FAMILIAR WITH BASIC CONCEPTS OF BIOPHARMACEUTICS AND PHARMACOKINETICS (I.E., THE MEANINGS OF ADME AND RELATED APPLICATIONS) 
預期每週課後學習時數
  
Office Hours
  
指定閱讀
 待補 
參考書目
 WAGNER, FUNDAMENTAL OF CLINICAL PHARMACOKINETICS, 1975
ROWLAND AND TOZER, CLINICAL PHARMACOKINETICS, CONCEPTS AND APPLICATIONS, 1995
IN ADDITION TO THE RECOMMENDED TEXTS ABOVE, READINGS FROM OTHER BOOKS, REVIEW ARTICLES OR THE PRIMARY LITERATURE MAY BE ASSIGNED OR RECOMMENDED BY EACH INSTRUCTOR. SOME OF THE FACULTY MAY ALSO PROVIDE HANDOUT NOTES AS A GUIDE OR SUPPLEMENT TO THEIR LECTURES. 
評量方式
(僅供參考)
    
課程進度
週次
日期
單元主題
第1週
 9/14  Pharmacogenetics and individualization 
第2週
 9/21  Drug-drug Interaction 
第3週
 9/28  Clinical application of population PK/PD analysis 
第4週
 10/05  Clinical Pharmacokinetics of Immunosuppressants 
第5週
 10/12  Clinical pharmacokinetics of CNS drugs 
第6週
 10/19  Clinical pharmacokinetics and medication use in pediatric patients 
第7週
 10/26  PK & PD of Antimicrobial agents 
第8週
 11/02  Aminoglycosides
(課前影片：https://goo.gl/KnWvJt） 
第9週
 11/09  Glycopeptides
(課前影片：https://goo.gl/ek9c5M) 
第10週
 11/16  Pharmacokinetic Basis For Dosing Adjustment in Renal Dialysis Patients 
第11週
 11/23  Clinical Pharmacokinetics in cardiac failure patients and cardiovascular drugs 
第12週
 11/30  Clinical Pharmacokinetics and chemotherapy 
第13週
 12/07  Antifungal agents 
第14週
 12/14  － 
第15週
 12/21  Effect of Hepatic Disease on Clinical Pharmacokinetics
－ Adjust Dosage in Hepatic Patients 
第16週
 12/28  (1) TDM in special populations: cancer patients
(2) Plasma Protein Binding on Clinical Pharmacokinetics 
第17週
 1/04  Clinical pharmacokinetics in geriatrics 
第18週
 1/11  期末考